Lesinurad

A phase 1 drug-drug interaction study to evaluate the potential effect of CYP2C9 inhibition and induction on the pharmacokinetics of lesinurad in healthy adult male subjects

A phase 1, randomized, double-blind, placebo-controlled study to evaluate safety, tolerability, pharmacokinetics, and pharmacodynamics of single and multiple doses of lesinurad in healthy male japanese subjects

A phase 1, single-dose, pharmacokinetic and pharmacodynamic study of lesinurad in male subjects with various degrees of hepatic impairment

A long-term extension study of lesinurad in combination with allopurinol for subjects completing an efficacy and safety study of lesinurad and allopurinol

A phase 3 randomized, double-blind, multicenter, placebo-controlled, combination study to evaluate the efficacy and safety of lesinurad and allopurinol compared to allopurinol alone in subjects with gout who have had an inadequate hyperuricemic response to standard of care allopurinol